International: Getting Started

Read about Cylex compliance with the In Vitro Diagnostic Directive.

The ImmuKnow assay can be performed within institutional laboratories such as hospitals, or can be sent to a reference laboratory. Typically, Cylex utilizes distributors to develop ImmuKnow testing internationally. Please feel free to contact the international distributors that provide ImmuKnow services in your region. Alternatively, please contact Cylex Customer Care to discuss laboratory requirements for the Cylex Training and Installation necessary for ImmuKnow adoption at your testing laboratory. Prior to your institution’s first order of the test, contact your local reference laboratory to establish special sample collection and transportation arrangements that must be observed in order to obtain acceptable results.

Download International Distributors List

Equipment Details

Luminometers

ImmuKnow is measurable on a variety of commercial luminometers. The major differences among luminometers are software programmability and presence or absence of injectors. The amount of light measured by a luminometer is proportional to the concentration of ATP in the biochemiluminescence reaction (luciferin/luciferase).

Because the ATP reaction in the ImmuKnow assay produces a stable glow reaction, injectors are not required. Therefore, if cost is a concern, selecting a luminometer without injectors will be an economical choice.

A luminometer that is compatible with the ImmuKnow Assay is capable of measuring chemiluminescence in RLU’s to detect ATP generation and meets the required specifications listed in the Package Insert.There are several luminometers that will support our assay; however, Cylex tested and selected a luminometer to be included in the Equipment Package.  Our Equipment Package includes one of the most affordable products on the market that maintains convenience, performance and reliability. 

Special agreements have been established with selected equipment suppliers to provide the majority of the required components in our Equipment Package to Cylex Customers.  The required incubator and general lab supplies should be obtained separately.  For this reason, we urge you to contact your local Business Development Manager or  Customer Care (Mike, hyperlink this to contact information, or email?)  when considering a luminometer purchase.

Microplate Shakers

There are many types of microtiter plate shakers available today. A plate shaker that is compatible with the ImmuKnow assay is specifically designed for use with 96-well microtiter plates and has an adjustable speed up to 1100 rpm. An orbital platform rotator will not suffice.

Because different shaker models have slight differences in mixing efficiency, the shaker speed which will support the ImmuKnow assay will need to be in the 800-1100 rpm range.

For these reasons among others, Cylex requires the use of the Siemens MicroMix5 microtiter plate shaker.  If other plate shakers are substituted, results are likely to be inconsistent.  Other problems found with using another shaker include a dial-up rpm (speed) is too subjective, and an uneven shaking speed across the platform is incompatible with our sensitive assay.

New Customer Set Up

Prior to processing your requests for shipment of equipment and ImmuKnow product, we will request your institution’s business information and your testing laboratory’s contact information.

Customer set up forms can be completed electronically and sent to Customer Care.